Patients battling HR-positive, HER2-negative metastatic breast cancer have a new therapeutic option following the FDA's accelerated approval of AstraZeneca’s Etcamah. The treatment, administered alongside a CDK4/6 inhibitor, specifically targets those whose tumors have developed ESR1 mutations during their initial course of standard hormone-based therapy.
With government debt on a clear downward trajectory, Fitch Ratings has upgraded Portugal’s long-term issuer default rating from A to A+. The decision underscores a broader shift in the country's economic standing, driven by sustained fiscal discipline that sets the nation apart from many of its European counterparts.
The Bancorp Bank will eliminate 64 positions, roughly 9% of its total workforce, as the institution shutters new loan originations for retail and wholesale customers by year-end. This restructuring marks a sharp shift toward fintech-focused operations, leaving existing small business clients to be managed through their current service agreements.
A high-stakes Phase 3 trial for Novartis’s heart disease treatment, pelacarsen, has failed to meet its primary objective. The drug did not demonstrate a significant reduction in major cardiovascular events—such as strokes, heart attacks, and fatalities—when measured against a placebo, marking a setback for the company’s cardiac pipeline.
Philippe Chevrier will vacate his position as Chief Operating Officer of Silgan Holdings on September 30. The packaging manufacturer confirmed the departure in a regulatory filing, noting that the decision to part ways was reached through a mutual agreement between the executive and the company leadership.
A high-stakes Phase 3 clinical trial for pelacarsen has failed to meet its primary objective, delivering a significant setback to Novartis. The medication, designed to prevent cardiovascular events like heart attacks and strokes, showed no statistical advantage over a placebo, prompting a sharp drop in company shares.
Jonathan Warkins has resigned as chief operating officer of SmartKem, effective August 31, marking a sudden exit just five months after his appointment. The company confirmed the departure was not prompted by disputes over internal operations or financial reporting, leaving the leadership team in flux during a period of extreme volatility.
Tata Motors has initiated an all-cash voluntary tender offer for Iveco Group, proposing 14.10 euros per share in a deal valuing the Italian vehicle manufacturer at approximately 3.82 billion euros. The move aims to bring the company under private ownership and delist it from the Euronext Milan exchange.
Unexpectedly strong employment figures for August triggered a sell-off in U.S. equities, as traders recalibrated their expectations for Federal Reserve policy. With employers adding 162,000 jobs—tripling initial economic forecasts—the sudden labor market surge has pushed Treasury yields toward 52-week highs and reignited concerns over persistent inflationary pressure.
Federal Housing Finance Agency Director Bill Pulte ignited a market sell-off Thursday night by labeling Fair Isaac a monopoly and threatening to overhaul the mortgage lending landscape. His public rebuke of credit bureaus and the dominance of FICO scores sent industry stocks into a sharp, sudden retreat during Friday morning trading.
Stanley Black & Decker is offloading its Excel Industries turf-care division to Bad Boy Mowers, a strategic divestiture aimed at concentrating capital on its core manufacturing brands. While the financial terms of the transaction remain undisclosed, the deal signals a shift toward sharpening the company's competitive focus in the industrial sector.
Arijit DasGupta is assuming direct control over both of Tredegar's core business units following the sudden departure of Bonnell Aluminum general manager Carl Czarnik. This move accelerates the manufacturer's transition from a traditional holding-company structure to a unified, streamlined operating model designed to eliminate redundant executive layers across the entire organization.
Bank7 shares climbed 8.1% to $56.70 on Friday after the firm emerged as the winning bidder for a controlling interest in Century Financial Services Corp. The acquisition, valued at $91 million, marks a significant expansion for the bank, which has already seen its stock value surge 38% throughout this year.
Shares of Silicon Motion Technology Corp. jumped 7.3% to $252.99 on Friday, marking a significant rally for a stock that has already surged 173% this year. The market responded to the company’s announcement that it has completed the initial phase of compliance with the European Union’s Cyber Resilience Act.
Shares of fleet management software provider Samsara rose 3.8% to $40.21 on Friday after the company reported a shift to profitability and raised its full-year guidance. The firm recorded a $16.2 million profit for the quarter ending August 1, a sharp turnaround from the $16.8 million loss reported one year ago.
Pro-Dex shares jumped 15% to $71.07 on Friday after the medical device manufacturer reported a 17% increase in fiscal fourth-quarter sales. This revenue spike, reaching $20.4 million, highlights the company's successful pivot back to high-volume production of a critical next-generation orthopedic handpiece for its primary customer.
A 16% drop in share price to $15.29 on Friday signals deep investor skepticism toward UiPath, despite the automation firm topping Wall Street’s quarterly earnings forecasts. While the company raised its annual outlook, market participants remain fixated on the looming threat of intensifying competition within the agentic artificial intelligence sector.
A surprise tariff refund and an upbeat sales forecast sent Torrid Holdings shares climbing 17% to $2.62 on Friday. The plus-size apparel retailer defied analyst expectations for a quarterly loss, marking a significant recovery that has pushed the stock price up by more than double since the start of the year.
Investors pushed New Pacific Metals shares down 4.5% to $6.40 on Friday after the Canadian exploration firm reported a net loss of $990,000 for the quarter ended June 30. The results disappointed the market, as analysts surveyed by FactSet had anticipated the company would break even on a per-share basis.
A $300 million capital injection has propelled San Francisco-based Gimlet Labs to a $3 billion valuation, marking a rapid ascent just five months after the company closed its initial funding round. The artificial intelligence research firm has now secured a total of $392 million to scale its specialized infrastructure.
With the Labor Day weekend underway, crude oil and diesel futures retreated on Friday morning, yet the broader market remains poised for weekly gains. Increased hostilities between the United States and Iran have kept volatility high, offsetting the immediate downward pressure on energy contracts heading into the holiday.
Quebecor shares climbed 1.9% to 63.11 Canadian dollars following a strategic sublicensing agreement with Rogers Communications. The Montreal-based media group will broadcast National Hockey League games in French, cementing its position in the sports market for over a decade through a deal spanning the 2026-27 to 2037-38 seasons.
Federal Housing Finance Agency Director Bill Pulte triggered a sharp market sell-off Thursday night, labeling credit bureaus a cartel and attacking Fair Isaac’s dominance in mortgage lending. His public condemnation, delivered via social media, immediately erased billions in combined market value for the industry’s most prominent players.
Shares of Houston-based Quanex Building Products climbed 18% to $22.14 on Friday morning, extending the company’s year-to-date gains to 44%. The rally follows a fiscal third-quarter report that revealed a return to profitability and a stabilization of margins following a challenging previous period.
Shares of Calgary-based energy infrastructure firm Keyera tumbled 4.7% on Friday morning, hitting 55.75 Canadian dollars, after management revised its annual marketing margin expectations downward. The company cited a combination of unexpected supply-chain disruptions and ongoing mechanical limitations as the primary drivers for the diminished financial forecast.
With competing buyout offers on the table, activist investor Radoff-JEC has demanded the immediate resignation of Seer board member Meeta Gulyani. The shareholder, which holds a 7.7% stake, claims Gulyani lacks the public board experience necessary to oversee the critical evaluation of acquisition bids for the life sciences firm.
A nonbinding letter of interest from the U.S. Export-Import Bank has opened a potential $750 million funding stream for Aclara Resources. The credit facility aims to bankroll Project Dynamo, a specialized rare-earth separation and metals plant slated for construction at the Port of Vinton, Louisiana.
Canada shed 41,700 net jobs in August, defying market forecasts of modest growth and reversing the momentum of a strong July. Despite the contraction in the workforce, the national unemployment rate remained anchored at 6.4%, reflecting a simultaneous cooling in the number of people actively seeking employment.
Norwegian oil producer DNO has officially abandoned its pursuit of Genel Energy, citing the U.K. firm's refusal to engage in merger discussions. The decision follows a rejected 202 million-pound takeover proposal and the expiration of a critical regulatory deadline mandated by British takeover rules.
A $25 million capital infusion will expand Pratt & Whitney’s manufacturing footprint in Niepolomice, Poland, adding over 120 jobs to the regional economy. The site, which specializes in complex tubular assemblies for both commercial and military aviation, targets full operational capacity by 2028 under the Polish Investment Zone Program.
